by Phillip Day

All our research, every­thing in our clin­i­cal expe­ri­ence over the past twenty-five years, has con­vinced us that you can improve your emo­tional state by improv­ing your nutri­tion; by mak­ing sure that every body cell receives opti­mal amounts of every essen­tial nutrient.”

- Cheraskin, Rings­dorf and Brecher, authors of Psy­chodi­etet­ics


Pre­vi­ously with depres­sion we exam­ined the effects of high lev­els of the neu­ro­trans­mit­ter his­t­a­mine, which is used by the brain to reg­u­late water usage, tears, mucus, saliva and other bod­ily secre­tions. Equally, low lev­els of this neu­ro­trans­mit­ter may also cre­ate prob­lems often linked to schiz­o­phre­nia. This con­di­tion is known as histapenia.


Undue sus­pi­cion and para­noia of peo­ple. The abil­ity to with­stand pain well. Hir­sutism (heavy growth of hair). Hard to achieve orgasm. Canker sores. Pho­bias and fears. Abnor­mal sen­sory per­cep­tions – see­ing and hear­ing things. Ring­ing in the ears (tin­ni­tus). Exces­sive den­tal fill­ings. An absence of headaches and allergies.

Low his­t­a­mine is often accom­pa­nied by high lev­els of cop­per, two fac­tors in them­selves which may pro­duce abnor­mal behav­iour. Many stud­ies over the years have gauged the cor­re­la­tion between excess cop­per and behav­ioural abnor­mal­i­ties. Dr Michael Briggs from Welling­ton, New Zealand, for instance, pos­tu­lated that many cases of schiz­o­phre­nia could merely be cop­per poi­son­ing. Dr Carl Pfeif­fer stud­ied the con­nec­tion between histape­nia, cop­per and behav­ioural prob­lems with his patients for many years. He reports that a sub-group of around 50% of his schiz­o­phrenic patients were high in cop­per. Pfeif­fer also noted that low lev­els of zinc and man­ganese were also impli­cated and that excess cop­per depresses his­t­a­mine and can be impli­cated in cop­perised pipes which bring water into house­holds. Abnor­mal lead and mer­cury lev­els are also well known to pro­duce schiz­o­phrenic symptoms.

Histapenia-pellagra-estrogen link

Sev­eral stud­ies have seen a link between pel­la­gra, the clas­sic vit­a­min B-3 defi­ciency dis­ease, and excess cop­per. Doc­tors Find­d­lay and Ven­ter dis­cov­ered that pel­la­gra patients were also high in cop­per. Dr Krish­nam­machavi dis­cov­ered this con­nec­tion in India in 1974 and found that vit­a­min B-3 appeared to reg­u­late cop­per lev­els in the body.1 Vit­a­min C defi­ciency also seemed to raise cop­per lev­els, which in turn pro­duced a vicious spi­ral, since excess cop­per is known to destroy vit­a­min C. Thus a com­bined defi­ciency in B-3 and C works to ele­vate cop­per lev­els in the body, which in turn destroy fur­ther sup­plies of vit­a­min C.

Histapenic modal­ity

Excess or dom­i­nant lev­els of the female sex hor­mone estro­gen, which brings on the clas­sic menopausal symp­toms such as hot flushes, depres­sion and mood swings, are also known to raise cop­per lev­els, which in turn deplete Vit­a­min C. In the sec­tion on Heart dis­ease in this book, we exam­ine the con­nec­tion between heart dis­ease and deple­tion of vit­a­min C (scurvy), brought on by the dis­solv­ing of col­la­gen, a tough, fibrous mate­r­ial which struc­tures the car­dio­vas­cu­lar sys­tem. In the 1960s, when the first con­tra­cep­tive pill, Envoid, was intro­duced, healthy young women began dying from throm­bo­sis. The con­tra­cep­tive pill, with its ele­vated lev­els of estro­gen, raises cop­per lev­els and depletes vit­a­min C. This excess of cop­per in turn depresses lev­els of his­t­a­mine. Low lev­els of his­t­a­mine pro­duce inad­e­quate lev­els of saliva, which in turn fail to pro­tect the teeth from bac­te­r­ial decay.

Take action!

By restor­ing the bal­ance of nutri­ents in the body, his­t­a­mine can be brought to nor­mal lev­els and the patient will expe­ri­ence relief from their symp­toms. Any patient suf­fer­ing from pho­bias, fears, hal­lu­ci­na­tions, or exhibit­ing many of the symp­toms described ear­lier, can obtain a blood test to track lev­els of cop­per and his­t­a­mine to deter­mine whether they are histapenic. Histapenic patients may ben­e­fit from the following:

  • DIET: COMMENCE THE FOOD FOR THOUGHT LIFESTYLE REGIMEN, increas­ing pro­tein in diet. Ensure 80% of the diet is plant-based and organic, with 80% eaten raw. Oily fish (cold-caught (not farmed) salmon, her­ring, mack­erel, etc.) and other foods con­tain­ing the essen­tial fats should be con­sumed. Take spe­cial note of the Foods to avoid sec­tion
  • DIET: Com­mence juic­ing organic veg­eta­bles and drink two/three glasses a day
  • VITAL: Increase water intake to A MINIMUM OF four pints (2 litres) per day
  • VITAL: Half a tea­spoon (tsp) of unre­fined sea salt or, best, Himalayan salt for every ten glasses of water, taken straight into the mouth in the morn­ing (NOT sodium chlo­ride, an indus­trial poi­son). Sprin­kle a few flakes on your tongue and allow to melt upon retiring
  • Oil Pulling, upon ris­ing, and last thing before bed (see A Guide to Nutri­tional Sup­ple­ments: Oil pulling before tak­ing)
  • Vit­a­min C com­plex, 25–30 g/day (see A Guide to Nutri­tional Sup­ple­ments: Vit­a­min C before tak­ing)
  • Opti­mise vit­a­min D serum level to 150 nmol/L (see A Guide to Nutri­tional Sup­ple­ments: Vit­a­min D-3 before tak­ing)
  • Niacin, (vit­a­min B-3): start at 200 mg, am and pm, and work through the skin flush, increas­ing up to 800 – 1,000 mg per day over time (see A Guide to Nutri­tional Sup­ple­ments: Vit­a­min B-3 before tak­ing)
  • Folic acid (vit­a­min B-9), 1,000 mcg each am
  • Vit­a­min B-12 injec­tion, weekly or daily supplementation
  • L-tryptophan, 1,000 mg at bedtime
  • Zinc and man­ganese daily, as directed by your physician
  • EARTHING: Spend fif­teen min­utes a day bare­foot on grass or a beach to allow a flow of antioxidant-acting free elec­trons into the body (see A Guide to Nutri­tional Sup­ple­ments: Earth­ing). It’s also worth get­ting a ground­ing sheet or bed mat to earth your­self while you sleep
  • REST: Max­imise mela­tonin pro­duc­tion by review­ing sleep­ing and light­ing arrange­ments (see A Guide to Nutri­tional Sup­ple­ments: Mela­tonin)

Excerpted from The ABC’s of Dis­ease updated 2013 edition

1 Krish­nam­machavi K, Am. J. Clin. Nutr., 1974, 27:108–111